ISSN :2583-424X
Zhao Zhang and Hongbo Wu
Adv. Artif. Intell. Mach. Learn., 1 (1):1-9
Zhao Zhang : Qinzhou Maternal and Child Health Care Hospital 1 Anzhou Avenue, Qinzhou CityQinzhouGuangXi China
Hongbo Wu : Phd
DOI: https://dx.doi.org/10.56439/JCMSR.2022.1101
Article History: Received on: 10-Mar-22, Accepted on: 20-Mar-22, Published on: 31-Mar-22
Corresponding Author: Zhao Zhang
Email: 2909969393@qq.com
Citation: Zhao Zhang (2022). A case report of primary infertility with BPES syndrome with FOXL2 gene mutation and PADI6 gene mutation. Adv. Artif. Intell. Mach. Learn., 1 (1 ):1-9
Human forkhead boxl2
(FOXL2) gene is closely related to female ovarian function. Mutations in FOXL2
gene often lead to BPES syndrome. BPES is divided into POF (BPES type I) and
non POF (BPES type II). This case report shows that when FOXL2 gene is combined
with PADI6 gene mutation, the patient may have obstacles to egg maturation in
addition to premature ovarian failure, resulting in the inability of the
patient to obtain embryos during art, which eventually leads to the inability
of the patient to obtain pregnancy.